Microbiologists describe new insights into human neurodegenerative disease
Microbiology researchers at the University of Georgia studying a soil bacterium have identified a potential mechanism for neurodegenerative diseases.
View ArticleRapamycin prevents Parkinson's in mouse model of incurable neurodegenerative...
Rapamycin, an FDA-approved drug that extends lifespan in several species, prevented Parkinson's disease (PD) in middle-age mice that were genetically fated to develop the incurable neurodegenerative...
View ArticleNot all organs age alike
Aging is typically thought of as the gradual decline of the whole body, but new research shows that age affects organs in strikingly different ways. A study published September 17 in Cell Systems...
View ArticleNew technique lets scientists see and study the interface where two cells touch
Interactions between brain cells hold the key to healthy brain function and cognition, but many of those interactions are notoriously difficult to study.
View ArticleCabozantinib improves survival in patients with advanced kidney cancer
Vienna, Austria: Patients with advanced kidney cancer live for nearly twice as long without their disease progressing if they are treated with cabozantinib, a drug that inhibits the action of tyrosine...
View ArticleScientists identify potential therapeutic target for pulmonary hypertension
Cardiovascular diseases are the leading cause of death worldwide. As a prime example, pulmonary hypertension is especially lethal, with one-half of patients dying within three years of being diagnosed....
View ArticleThe brain forgets in order to conserve energy
Our brains not only contain learning mechanisms but also forgetting mechanisms that erase "unnecessary" learning. A research group at Lund University in Sweden has now been able to describe one of...
View ArticleBipolar patients' brain cells predict response to lithium
The brain cells of patients with bipolar disorder, characterized by severe swings between depression and elation, are more sensitive to stimuli than other people's brain cells, researchers have...
View ArticleBiologics for asthma: Attacking the source of the disease, not the symptoms
Imagine you suffer from severe asthma, and you've tried every treatment available, but nothing has worked. You still can't breathe. Then a new therapy comes along that attacks the source of the asthma,...
View ArticleEstrogen receptor 'beta' helps endometrial tissue escape the immune system...
Endometriosis - tissue usually found inside the uterus that grows outside - thrives because of altered cellular signaling that is mediated by estrogen, said researchers from Baylor College of Medicine...
View ArticleSignaling from dysfunctional mitochondria induces a distinct type of senescence
Buck Institute faculty Judith Campisi, PhD, says age researchers need to stop thinking of cellular senescence, now accepted as an important driver of aging, as a single phenotype that stems from...
View ArticleMinding the gap: International team defines spaces through which nerve cells...
In a report published in the journal Neuron, an international team of researchers defined the makeup of the cellular structures through which nerve cells communicate with each other. These "synaptic...
View ArticleProstate cancer discovery may make it easier to kill cancer cells
A newly discovered connection between two common prostate cancer treatments may soon make prostate cancer cells easier to destroy. Drugs that could capitalize on the discovery are already in the...
View ArticleImmunotherapy for Epstein-Barr related lymphomas
Imagine that your immune system could be educated so that it was able to recognize specific diseases and then destroy them. Science fiction? Or perhaps futuristic? Not anymore.
View ArticleResearch reveals connection between tauopathies and disruption in protein...
Assistant Professor Joe Abisambra, researcher at the University of Kentucky Sanders-Brown Center on Aging, has demonstrated for the first time that tau impairs protein synthesis—a key component in...
View ArticleStudy identifies enzyme key to link between age-related inflammation and cancer
For the first time, researchers have shown that an enzyme key to regulating gene expression—and also an oncogene when mutated—is critical for the expression of numerous inflammatory compounds that have...
View ArticleMitochondria trigger cell aging, study shows
An international team of scientists has for the first time shown that mitochondria, the batteries of the cells, are essential for ageing.
View ArticleTeam develops approach for identifying processes that fuel tumor growth in...
Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have pioneered a new method for conducting in-depth research on malignant tumors in patients, in the process...
View ArticleAggression causes new nerve cells to be generated in the brain
A group of neurobiologists from Russia and the USA, including Dmitry Smagin, Tatyana Michurina, and Grigori Enikolopov from Moscow Institute of Physics and Technology (MIPT), have proven experimentally...
View ArticleNew analysis method may reduce need for invasive biopsies
Scientists have identified a quantitative method to measure changes in biomarkers, which may reduce or eliminate the need for invasive biopsies. The method, described in the February 2016 issue of The...
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