In a report published in the journal Neuron, an international team of researchers defined the makeup of the cellular structures through which nerve cells communicate with each other. These "synaptic clefts" are the small gaps between nerve cells (neurons) that relay information in the brain. Synapses, including the synaptic clefts, are formed rapidly shortly before and after birth. Mutations in the proteins that make up the cleft increase vulnerability to developmental disorders, notably autism spectrum disorders.
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