More evidence shows natural plant compound may reduce mental effects of aging
Salk scientists have found further evidence that a natural compound in strawberries reduces cognitive deficits and inflammation associated with aging in mice. The work, which appeared in the Journals...
View ArticleNew data network for Huntington's disease research
Huntington's disease is an hereditary disorder of the nervous system caused by a faulty gene on chromosome four. The faulty gene leads to cell death in neurons in the brain resulting in gradual...
View ArticleImmune cells the missing ingredient in new bladder cancer treatment
New research offers a possible explanation for why a new type of cancer treatment hasn't been working as expected against bladder cancer.
View ArticleResearchers develop technology to make aged cells younger
Aging. We all face it. Nobody's immune and we've long tried to reverse it, stop it or just even slow it down. While advances have been made, true age-reversal at a cellular level remains difficult to...
View ArticleTeam identifies weight-gain receptor linked to antipsychotic drugs
Many schizophrenic and depressed patients experience weight gain and type 2 diabetes in their quests for the life-changing benefits of a major class of antipsychotic drugs.
View ArticleResearch reveals how estrogen regulates gene expression
Estrogen hormones regulate gene expression. They achieve this by first binding to estrogen receptor in the cell nucleus, which triggers the recruitment of different molecules called coactivators in...
View ArticleScientists find interaction between two key proteins regulates development of...
Salk Institute scientists have discovered that an interaction between two key proteins helps regulate and maintain the cells that produce neurons. The work, published in Cell Stem Cell on September 14,...
View ArticleNew studies add to understanding of treatments for Barrett's esophagus
The October issue of GIE: Gastrointestinal Endoscopy features several new studies evaluating various treatments for Barrett's esophagus (BE). Two of these studies are highlighted below.
View ArticleScientists discover novel mechanism that protects mitochondrial DNA
Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close collaboration...
View ArticleScientists pinpoint surprising origin of melanoma
Led by Jean-Christophe Marine (VIB-KU Leuven), a team of researchers has tracked down the cellular origin of cutaneous melanoma, the deadliest form of skin cancer. The team was surprised to observe...
View ArticleCalcium intake and colorectal cancer
Calcium plays key roles in cellular signaling, proliferation and death. Previous studies exploring the relationship between dietary calcium intake and colorectal cancer have had contradictory results,...
View ArticleResearchers study cellular processes dependent on calcium ions
Calcium-ATPases convey calcium ions (Ca2+) from the cytoplasm to the extracellular space via active transport (using ATP as an energy source), and thus fundamentally contribute to the control of a wide...
View ArticleNeuroscientists build case for new theory of memory formation
Learning and memory are generally thought to be composed of three major steps: encoding events into the brain network, storing the encoded information, and later retrieving it for recall.
View ArticleHow to turn damaged heart tissue back into healthy heart muscle—new details...
Reversing scar tissue after a heart attack to create healthy heart muscle: this would be a game-changer in the field of cardiology and regenerative medicine. In the lab, scientists have shown it's...
View ArticleNew study identifies targets to lessen the effects of alcoholic liver disease
In 2015, nearly half of 80,000 deaths due to liver diseases in the United States were related to alcoholic liver disease (ALD), according to the National Institute on Alcohol Abuse and Alcoholism....
View ArticleMisregulated protein breakdown promotes leukemias and brain cancer
An enzyme that is responsible for the breakdown of specific amino acids in food plays a key role in the development of leukemias and brain cancer, according to scientists from the German Cancer...
View ArticleResearchers identify a key nutrient sensor in the mTOR pathway that links...
To survive and grow, a cell must properly assess the resources available and couple that with its growth and metabolism—a misstep in that calculus can potentially cause cell death or dysfunction. At...
View ArticleSome chemicals in smoke may be even more dangerous than previously thought
It's no surprise that chemicals in smoke cause cancer, but a new study published in the Archives of Toxicology shows that some chemicals in cigarette smoke and industrial processes may be more...
View ArticleNew clues to Alzheimer's disease
Researchers probing the complexities of Alzheimer's disease have detected issues involving cellular energy production, and those problems may be an important contributor to the late-onset form of the...
View ArticleResearchers pinpoint pathway to muscle paralysis
Researchers at the University of Arizona have taken an essential step forward in the quest to find the cause of amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease. In the cells of...
View ArticleResearchers use breakthrough technology to understand eclipse eye damage
In a first-of-its-kind study, Mount Sinai researchers are using adaptive optics (AO) to analyze retinal eye damage from the August solar eclipse on a cellular level. The research could help doctors...
View ArticleNew findings show what develops in body cells during type 2 diabetes onset
Researchers at Dublin City University and their project partners in the EU FP7 funded DEXLIFE project have found fresh evidence to explain the processes that occur in the body's cells leading to the...
View ArticleNew 'checkpoint' model that could identify potential drugs to treat genetic...
A new 'checkpoint' model which can be used to identify potential treatments for genetic disorders such as cystic fibrosis and Duchenne muscular dystrophy (DMD) has been proposed by a team of Bradford...
View Article'Immunomap' suggests more is better when it comes to immune cell receptors...
Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical "antennas" on the surface of immune system T-cells. Their...
View ArticleScientists discover molecule that could revert celular ageing
Researchers at Instituto de Medicina Molecular (iMM) João Lobo Antunes have found that manipulating a single RNA molecule is enough to revert cellular aging.
View ArticleMetabolic pathway involved in immune response to Zika also participates in...
Researchers at the University of Campinas (UNICAMP) in São Paulo State, Brazil, have identified molecules that serve as markers of Zika in blood serum taken from patients with this viral infection.
View ArticleInsights into the molecular mechanisms leading to kidney dysfunction in...
About one-third of diabetes patients suffer from renal failure. Therefore, understanding the mechanisms linking diabetes to renal damage (diabetic nephropathy) would benefit patients as it would help...
View ArticleLongevity insights from demographic, phenotypic and genetic studies
Understanding the demographic, phenotypic and genetic features associated with ageing has been the subject of many studies worldwide. Japan offers a unique opportunity for such studies since it has a...
View ArticleModulating molecules: Study shows oxytocin helps the brain to modulate social...
Between sights, sounds, smells and other senses, the brain is flooded with stimuli on a moment-to-moment basis. How can it sort through the flood of information to decide what is important and what can...
View ArticleResearch reveals atomic-level changes in ALS-linked protein
For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia...
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