Team releases gene edited human stem cell lines
The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that...
View ArticleHow the tuberculosis vaccine may protect against other diseases
The tuberculosis vaccine is well known to help protect against other infectious diseases, as well as cancer, but the exact mechanisms have not been clear. A study published December 6 in Cell Reports...
View ArticleScientists discover a molecular trigger of fat-cell 'browning' program
A signaling pathway in fat cells may one day provide the key to better treatments for obesity, according to new research by scientists in the Perelman School of Medicine at the University of...
View ArticleCellular reprogramming reverses signs of aging
Graying hair, crow's feet, an injury that's taking longer to heal than when we were 20—faced with the unmistakable signs of aging, most of us have had a least one fantasy of turning back time. Now,...
View ArticleNew construction role found for cell demolition tool
A new role has been discovered for a well-known piece of cellular machinery, which could revolutionise the way we understand how tissue is constructed and remodelled within the body.
View ArticleScientists uncover cellular process behind premature aging
In a new study, scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown how two genes "balance" each other to maintain normal cell function. A disruption in one of the...
View ArticleThirteen ways to keep free radicals away, and why it's so important
The holiday season is in full swing, and with it comes time for family celebration while gathering around tables full of delicious foods with seasonal spices! But it can also be a stressful time of...
View ArticleResearch reveals the importance of long non-coding RNA regulating cellular...
Scientific research over the past decade has concentrated almost exclusively on the 2 percent of the genome's protein coding regions, virtually ignoring the other 98 percent, a vast universe of...
View ArticleSenescence promotes chemotherapy side effects and cancer relapse
Standard chemotherapy is a blunt force instrument against cancer – and it's a rare cancer patient who escapes debilitating side effects from systemic treatments that mostly affect dividing cells, both...
View ArticleScientists discover drug that increases 'good' fat mass and function
Scientists at the Gladstone Institutes identified an FDA-approved drug that can create the elusive and beneficial brown fat. Mice treated with the drug had more brown fat, faster metabolisms, and lower...
View ArticleWhat causes sleepiness when sickness strikes
It's well known that humans and other animals are fatigued and sleepy when sick, but it's a microscopic roundworm that's providing an explanation of how that occurs, according to a study from...
View ArticleAs cells age, the fat content within them shifts
As cells age and stop dividing, their fat content changes, along with the way they produce and break down fat and other molecules classified as lipids, according to a new University at Buffalo study.
View ArticleNew study shows how to avoid weight gain and cardiometabolic disease
To explain why so many people in developed countries are chronically overfed, tend to accumulate fat, and are at increased risk for cardiometabolic disease, researchers suggest looking no further than...
View ArticleCellular quality control process could be Huntington's disease drug target
The loss of motor function and mental acuity associated with Huntington's disease might be treatable by restoring a cellular quality control process, which Duke Health researchers have identified as a...
View ArticleStudy reveals PGK1 enzyme as therapeutic target for deadliest brain cancer
Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic target for glioblastoma, an often fatal form of brain cancer, according to researchers at...
View ArticleBoosting your own defenses against heart disease
A protein found in the heart that is known to be involved in cellular stress responses in cancer cells is now believed to play a critical role in the ability of cardiac cells to combat heart disease...
View ArticleResearchers examine molecular-level problems of heart disease
Researchers are one step closer to understanding heart disease at a microscopic level, a breakthrough that could influence future treatments for millions of people.
View ArticleHow exercise—interval training in particular—helps your mitochondria stave...
It's oft-repeated but true: exercise keeps you healthy. It boosts your immune system, keeps the mind sharp, helps you sleep, maintains your muscle tone, and extends your healthy lifespan. Researchers...
View ArticleCellular senescence prevented by the SETD8 enzyme
An enzyme that blocks cellular senescence and its mechanisms has been discovered by a research team from Kumamoto University, Japan. They found that a reduction of the enzyme SETD8, which regulates...
View ArticleDisrupting prostate cancer 'homing signal' could hold promise for new treatments
New King's College London research sheds light on the cellular mechanisms which enable cancer cells to escape the prostate and spread to other parts of the body.
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