Research reveals atomic-level changes in ALS-linked protein
For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia...
View ArticleModulating molecules: Study shows oxytocin helps the brain to modulate social...
Between sights, sounds, smells and other senses, the brain is flooded with stimuli on a moment-to-moment basis. How can it sort through the flood of information to decide what is important and what can...
View ArticleLongevity insights from demographic, phenotypic and genetic studies
Understanding the demographic, phenotypic and genetic features associated with ageing has been the subject of many studies worldwide. Japan offers a unique opportunity for such studies since it has a...
View ArticleInsights into the molecular mechanisms leading to kidney dysfunction in...
About one-third of diabetes patients suffer from renal failure. Therefore, understanding the mechanisms linking diabetes to renal damage (diabetic nephropathy) would benefit patients as it would help...
View ArticleMetabolic pathway involved in immune response to Zika also participates in...
Researchers at the University of Campinas (UNICAMP) in São Paulo State, Brazil, have identified molecules that serve as markers of Zika in blood serum taken from patients with this viral infection.
View ArticleScientists discover molecule that could revert celular ageing
Researchers at Instituto de Medicina Molecular (iMM) João Lobo Antunes have found that manipulating a single RNA molecule is enough to revert cellular aging.
View Article'Immunomap' suggests more is better when it comes to immune cell receptors...
Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical "antennas" on the surface of immune system T-cells. Their...
View ArticleNew 'checkpoint' model that could identify potential drugs to treat genetic...
A new 'checkpoint' model which can be used to identify potential treatments for genetic disorders such as cystic fibrosis and Duchenne muscular dystrophy (DMD) has been proposed by a team of Bradford...
View ArticleNew findings show what develops in body cells during type 2 diabetes onset
Researchers at Dublin City University and their project partners in the EU FP7 funded DEXLIFE project have found fresh evidence to explain the processes that occur in the body's cells leading to the...
View ArticleResearchers use breakthrough technology to understand eclipse eye damage
In a first-of-its-kind study, Mount Sinai researchers are using adaptive optics (AO) to analyze retinal eye damage from the August solar eclipse on a cellular level. The research could help doctors...
View ArticleResearchers pinpoint pathway to muscle paralysis
Researchers at the University of Arizona have taken an essential step forward in the quest to find the cause of amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease. In the cells of...
View ArticleNew clues to Alzheimer's disease
Researchers probing the complexities of Alzheimer's disease have detected issues involving cellular energy production, and those problems may be an important contributor to the late-onset form of the...
View ArticleSome chemicals in smoke may be even more dangerous than previously thought
It's no surprise that chemicals in smoke cause cancer, but a new study published in the Archives of Toxicology shows that some chemicals in cigarette smoke and industrial processes may be more...
View ArticleResearchers identify a key nutrient sensor in the mTOR pathway that links...
To survive and grow, a cell must properly assess the resources available and couple that with its growth and metabolism—a misstep in that calculus can potentially cause cell death or dysfunction. At...
View ArticleMisregulated protein breakdown promotes leukemias and brain cancer
An enzyme that is responsible for the breakdown of specific amino acids in food plays a key role in the development of leukemias and brain cancer, according to scientists from the German Cancer...
View ArticleNew study identifies targets to lessen the effects of alcoholic liver disease
In 2015, nearly half of 80,000 deaths due to liver diseases in the United States were related to alcoholic liver disease (ALD), according to the National Institute on Alcohol Abuse and Alcoholism....
View ArticleHow to turn damaged heart tissue back into healthy heart muscle—new details...
Reversing scar tissue after a heart attack to create healthy heart muscle: this would be a game-changer in the field of cardiology and regenerative medicine. In the lab, scientists have shown it's...
View ArticleNeuroscientists build case for new theory of memory formation
Learning and memory are generally thought to be composed of three major steps: encoding events into the brain network, storing the encoded information, and later retrieving it for recall.
View ArticleResearchers study cellular processes dependent on calcium ions
Calcium-ATPases convey calcium ions (Ca2+) from the cytoplasm to the extracellular space via active transport (using ATP as an energy source), and thus fundamentally contribute to the control of a wide...
View ArticleCalcium intake and colorectal cancer
Calcium plays key roles in cellular signaling, proliferation and death. Previous studies exploring the relationship between dietary calcium intake and colorectal cancer have had contradictory results,...
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